Particula

BY RESEARCHERS. FOR LABS.

NanoGlyph

Discover drugs faster.
Make your budget go further.

A nanosensor designed by researchers to help labs accelerate drug discovery at a lower cost.

Sounds like science fiction? Read on
Scroll to discover

THE PROBLEM

Discovery moves fast.
Testing holds it back.

Faster answers come at a price.
Lower budgets come with a wait.

The cost of answers

≈$45k

One study. A major investment.

Combining ELISA, imaging and omics adds up before the next decision can be made.

The cost of waiting

≈3 weeks

Every answer takes time.

Long testing cycles slow the experiments that could move a promising candidate forward.

Even in the best-case scenario. These illustrative estimates represent the lowest-cost scenario in Particula’s MVP model for an ELISA + imaging + omics workflow. Actual costs and timelines vary by study.

THE SOLUTION / NANOGLYPH

Small sensor.
Bigger perspective.

One connected platform. From molecular interactions
to a biological fingerprint you can explore.

01 / SENSE

Nanosensor

NanoGlyph turns dynamic molecular interactions into spectral fingerprints. No predefined biomarker required — so you can explore biology before you know exactly what to look for.

Molecular interactions

02 / READ

NIR plate reader

Capture the nanosensor’s near-infrared signal. Its optical, photostable readout can support repeated, time-resolved measurements when sample integrity is preserved.

Optical fingerprints

03 / INTERPRET

AI software

Explore patterns across spectra and time. Investigate multifactorial disease states, distinguish sample groups and compare drug responses within the context of your study.

Biological insight

Three components. One research workflow.

HOW IT WORKS

Biology speaks.
We read the signal.

From your sample to a dynamic molecular fingerprint.

Explore a pilot with your samples
  1. 01

    Introduce your sample

    Bring a relevant biological sample into contact with the nanosensors.

  2. 02

    Let interactions leave a signature

    Molecules interact with the sensor surface, changing the nanosensor’s optical response.

  3. 03

    Illuminate. Read. Repeat.

    Collect near-infrared spectra. Where sample integrity is preserved, repeated readings can reveal how the fingerprint evolves.

  4. 04

    Connect the patterns

    AI-assisted analysis explores spectral and temporal patterns to help compare samples, conditions and responses.

USE CASES

When one marker
isn’t the whole story.

Potential applications for complex biology.
Built to be explored with your research.

01Drug-response screening

Explore whether a treatment shifts a sample’s molecular fingerprint, and compare responses across candidate compounds or conditions.

02Complex disease biology

Study biology distributed across multiple molecular changes, especially when no single validated biomarker captures the full picture.

03Patient stratification research

Investigate whether spectral fingerprints distinguish biologically different sample groups that appear similar by other measures.

04Longitudinal monitoring

Follow changes over time with repeated optical measurements in assays designed to preserve sample integrity.

05Early phenotypic screening

Explore a broader molecular readout to help prioritize samples or conditions for deeper downstream characterization.

06Unknown biomarkers

Start exploring without choosing a protein to measure in advance. Capture a molecular fingerprint when the relevant biomarkers are still unknown.

FREE PILOT. SHARED PROGRESS.

Join the
pilot program.

Your lab wants to get ahead.
We need real-world data.

Explore NanoGlyph for free — and help shape what comes next.

FOR YOUR LAB

A head start on your next discovery.

Explore a new way to read your biology and see where NanoGlyph could add value to your workflow.

FOR NANOGLYPH

Real data. A stronger platform.

Your experiments and feedback help us evaluate NanoGlyph across real research questions and improve the platform.

Full-platform pilot

Partner Alpha

Available from

Explore the complete NanoGlyph workflow with your biological models.

We provide

  • Nanosensors
  • NIR plate reader
  • Integrated software / AI analysis

You bring

Relevant samples, assays or biological models.

Sensor-first pilot

Partner Beta

Available now

Bring NanoGlyph into a lab that already has NIR measurement capabilities.

We provide

  • Nanosensors

You bring

Relevant samples, assays or biological models, your own NIR plate reader and autonomous analysis.

Your next discovery starts with a conversation.

Join the free pilot

One form. Two ways to partner.
Tell us about your lab — we’ll define fit, scope and timing together.

LET’S TALK

What could your
samples tell you?

Bring us your research question.
Let’s explore it with NanoGlyph.

Contact us to know more

Email us at riccardo-s@uri.edu.